Chemopreventive Target for Prostate Cancer: Prostatic Intraepithelial Neoplasia
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چکیده
Prostate cancer is one of the most frequently diagnosed malignancies among the male population and the second common cancer-related death worldwide after lung cancer (Jemal et al., 2010). It is estimated that 30% of male older than 50 years are harboring microscopic transformation of adenocarcinoma within the prostate gland. Because of the dramatic rise in the incidence of prostate cancer with the rate increasing approximately 6% per year worldwide (Eschenbach, 1996), the study of precursor lesions of prostate cancer is emerging concept in the field of prostate cancer prevention.
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تاریخ انتشار 2012